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Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury

Angiotensin II causes cardiovascular injury in part by aldosterone-induced mineralocorticoid receptor activation, and it can also activate the mineralocorticoid receptor in the absence of aldosterone in vitro. Here we tested whether endogenous aldosterone contributes to angiotensin II/salt-induced c...

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Detalles Bibliográficos
Autores principales:	Luther, James M., Luo, Pengcheng, Wang, Zuofei, Cohen, Samuel E., Kim, Hyung-Suk, Fogo, Agnes B., Brown, Nancy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434275/ https://www.ncbi.nlm.nih.gov/pubmed/22622494 http://dx.doi.org/10.1038/ki.2012.170

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