Ablation of the calcium-sensing receptor in keratinocytes impairs epidermal differentiation and barrier function

The calcium-sensing receptor (CaR) plays an essential role in mediating Ca(2+)-induced keratinocyte differentiation in vitro. In this study, we generated keratinocyte-specific CaR knockout ((Epid)CaR-/-) mice to investigate the function of the CaR in epidermal development in vivo. (Epid)CaR-/- mice...

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Detalles Bibliográficos
Autores principales: Tu, Chia-Ling, Crumrine, Debra, Man, Mao-Qiang, Chang, Wenhan, Elalieh, Hashem, You, Michael, Elias, Peter M., Bikle, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434298/
https://www.ncbi.nlm.nih.gov/pubmed/22622426
http://dx.doi.org/10.1038/jid.2012.159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434298/
https://www.ncbi.nlm.nih.gov/pubmed/22622426
http://dx.doi.org/10.1038/jid.2012.159

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