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Development of CFTR Structure

Cystic fibrosis is a lethal genetic disease caused by lack of functional cystic fibrosis transmembrane conductance regulator (CFTR) proteins at the apical surface of secretory epithelia. CFTR is a multidomain protein, containing five domains, and its functional structure is attained in a hierarchica...

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Detalles Bibliográficos
Autores principales: Patrick, Anna E., Thomas, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434365/
https://www.ncbi.nlm.nih.gov/pubmed/22973227
http://dx.doi.org/10.3389/fphar.2012.00162