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AZT as a telomerase inhibitor

Telomerase is a highly specialized reverse transcriptase (RT) and the maintenance of telomeric length is determined by this specific enzyme. The human holoenzyme telomerase is a ribonucleoprotein composed by a catalytic subunit, hTERT, an RNA component, hTR, and a group of associated proteins. Telom...

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Detalles Bibliográficos
Autores principales: Gomez, Daniel E., Armando, Romina G., Alonso, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434370/
https://www.ncbi.nlm.nih.gov/pubmed/22973556
http://dx.doi.org/10.3389/fonc.2012.00113