Cargando…
AZT as a telomerase inhibitor
Telomerase is a highly specialized reverse transcriptase (RT) and the maintenance of telomeric length is determined by this specific enzyme. The human holoenzyme telomerase is a ribonucleoprotein composed by a catalytic subunit, hTERT, an RNA component, hTR, and a group of associated proteins. Telom...
Autores principales: | Gomez, Daniel E., Armando, Romina G., Alonso, Daniel F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434370/ https://www.ncbi.nlm.nih.gov/pubmed/22973556 http://dx.doi.org/10.3389/fonc.2012.00113 |
Ejemplares similares
-
Telomere structure and telomerase in health and disease
por: GOMEZ, DANIEL E., et al.
Publicado: (2012) -
Revitalizing the AZT Through of the Selenium: An Approach in Human Triple Negative Breast Cancer Cell Line
por: Wagner, Mônica Silveira, et al.
Publicado: (2018) -
Effect of 3`-Azido-3`-Deoxythymidine (AZT) on Telomerase Activity and Proliferation of HO-8910 Cell Line of Ovarian Cancer
por: Dinman, Jonathan D.
Publicado: (2006) -
Effect of 3`-Azido-3`-Deoxythymidine (AZT) on Telomerase Activity and Proliferation of HO-8910 Cell Line of Ovarian Cancer
por: Li, Hongmei, et al.
Publicado: (2006) -
Homology Model and Docking-Based Virtual Screening for Ligands of Human Dyskerin as New Inhibitors of Telomerase for Cancer Treatment
por: Armando, Romina Gabriela, et al.
Publicado: (2018)