Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. Although novel drugs against HCV are under development, the current standard therapy consists principally of interferon (IFN). To improve the response to IFN treatment by enhancing interferon-stimulated response e...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Takeshi, Takata, Akemi, Otsuka, Motoyuki, Kishikawa, Takahiro, Kojima, Kentaro, Yoshida, Haruhiko, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434395/
https://www.ncbi.nlm.nih.gov/pubmed/22957141
http://dx.doi.org/10.1038/srep00637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434395/
https://www.ncbi.nlm.nih.gov/pubmed/22957141
http://dx.doi.org/10.1038/srep00637

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