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Silencing of microRNA-122 enhances interferon-α signaling in the liver through regulating SOCS3 promoter methylation
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide. Although novel drugs against HCV are under development, the current standard therapy consists principally of interferon (IFN). To improve the response to IFN treatment by enhancing interferon-stimulated response e...
Autores principales: | Yoshikawa, Takeshi, Takata, Akemi, Otsuka, Motoyuki, Kishikawa, Takahiro, Kojima, Kentaro, Yoshida, Haruhiko, Koike, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434395/ https://www.ncbi.nlm.nih.gov/pubmed/22957141 http://dx.doi.org/10.1038/srep00637 |
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