Prolonged Action Potential and After depolarizations Are Not due to Changes in Potassium Currents in NOS3 Knockout Ventricular Myocytes

Ventricular myocytes deficient in endothelial nitric oxide synthase (NOS3(−/−)) exhibit prolonged action potential (AP) duration and enhanced spontaneous activity (early and delayed afterdepolarizations) during β-adrenergic (β-AR) stimulation. Studies have shown that nitric oxide is able to regulate...

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Detalles Bibliográficos
Autores principales: Wang, Honglan, Bonilla, Ingrid M., Huang, Xin, He, Quanhua, Kohr, Mark J., Carnes, Cynthia A., Ziolo, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434404/
https://www.ncbi.nlm.nih.gov/pubmed/22970362
http://dx.doi.org/10.1155/2012/645721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434404/
https://www.ncbi.nlm.nih.gov/pubmed/22970362
http://dx.doi.org/10.1155/2012/645721

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