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Inhibitory Effects of Daiokanzoto (Da-Huang-Gan-Cao-Tang) on P-Glycoprotein

We have studied the effects of various Kampo medicines on P-glycoprotein (P-gp), a drug transporter, in vitro. The present study focused on Daiokanzoto (Da-Huang-Gan-Cao-Tang), which shows the most potent inhibitory effects on P-gp among the 50 Kampo medicines studied, and investigated the P-gp inhi...

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Detalles Bibliográficos
Autores principales: Watanabe, Yuka, Ikarashi, Nobutomo, Satoh, Toshiyuki, Ito, Kiyomi, Ochiai, Wataru, Sugiyama, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434426/
https://www.ncbi.nlm.nih.gov/pubmed/22969825
http://dx.doi.org/10.1155/2012/361516