Localization of Association Signal from Risk and Protective Variants in Sequencing Studies

Aggregating information across multiple variants in a gene or region can improve power for rare variant association testing. Power is maximized when the aggregation region contains many causal variants and few neutral variants. In this paper, we present a method for the localization of the associati...

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Detalles Bibliográficos
Autores principales: Brisbin, Abra, Jenkins, Gregory D., Ellsworth, Katarzyna A., Wang, Liewei, Fridley, Brooke L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434438/
https://www.ncbi.nlm.nih.gov/pubmed/22973297
http://dx.doi.org/10.3389/fgene.2012.00173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434438/
https://www.ncbi.nlm.nih.gov/pubmed/22973297
http://dx.doi.org/10.3389/fgene.2012.00173

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