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Identification of binding pockets in protein structures using a knowledge-based potential derived from local structural similarities
BACKGROUND: The identification of ligand binding sites is a key task in the annotation of proteins with known structure but uncharacterized function. Here we describe a knowledge-based method exploiting the observation that unrelated binding sites share small structural motifs that bind the same che...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434446/ https://www.ncbi.nlm.nih.gov/pubmed/22536963 http://dx.doi.org/10.1186/1471-2105-13-S4-S17 |