MS-275 sensitizes osteosarcoma cells to Fas ligand-induced cell death by increasing the localization of Fas in membrane lipid rafts

Fas expression is inversely correlated with the metastatic potential of osteosarcoma (OS) cells to the lungs. Fas(+) cells are rapidly eliminated when they enter the lungs via their interaction with constitutive Fas ligand (FasL) on the lung epithelium, whereas Fas(−) OS cells escape this FasL-induc...

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Detalles Bibliográficos
Autores principales: Rao-Bindal, K, Zhou, Z, Kleinerman, E S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434650/
https://www.ncbi.nlm.nih.gov/pubmed/22875006
http://dx.doi.org/10.1038/cddis.2012.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434650/
https://www.ncbi.nlm.nih.gov/pubmed/22875006
http://dx.doi.org/10.1038/cddis.2012.101

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