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MS-275 sensitizes osteosarcoma cells to Fas ligand-induced cell death by increasing the localization of Fas in membrane lipid rafts
Fas expression is inversely correlated with the metastatic potential of osteosarcoma (OS) cells to the lungs. Fas(+) cells are rapidly eliminated when they enter the lungs via their interaction with constitutive Fas ligand (FasL) on the lung epithelium, whereas Fas(−) OS cells escape this FasL-induc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434650/ https://www.ncbi.nlm.nih.gov/pubmed/22875006 http://dx.doi.org/10.1038/cddis.2012.101 |