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Cre transgene results in global attenuation of the cAMP/PKA pathway
Use of the cre transgene in in vivo mouse models to delete a specific ‘floxed' allele is a well-accepted method for studying the effects of spatially or temporarily regulated genes. During the course of our investigation into the effect of cyclic adenosine 3′,5′-monophosphate-dependent protein...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434654/ https://www.ncbi.nlm.nih.gov/pubmed/22875002 http://dx.doi.org/10.1038/cddis.2012.110 |