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Cre transgene results in global attenuation of the cAMP/PKA pathway

Use of the cre transgene in in vivo mouse models to delete a specific ‘floxed' allele is a well-accepted method for studying the effects of spatially or temporarily regulated genes. During the course of our investigation into the effect of cyclic adenosine 3′,5′-monophosphate-dependent protein...

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Detalles Bibliográficos
Autores principales: Gangoda, L, Doerflinger, M, Lee, Y Y, Rahimi, A, Etemadi, N, Chau, D, Milla, L, O'Connor, L, Puthalakath, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434654/
https://www.ncbi.nlm.nih.gov/pubmed/22875002
http://dx.doi.org/10.1038/cddis.2012.110