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Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated Neuronal dysfunction

Neuronal damage is a hallmark feature of HIV-associated neurological disorders (HANDs). Opiate drug abuse accelerates the incidence and progression of HAND; however, the mechanisms underlying the potentiation of neuropathogenesis by these drugs remain elusive. Opiates such as morphine have been show...

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Detalles Bibliográficos
Autores principales: Hu, G, Yao, H, Chaudhuri, A D, Duan, M, Yelamanchili, S V, Wen, H, Cheney, P D, Fox, H S, Buch, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434655/
https://www.ncbi.nlm.nih.gov/pubmed/22932723
http://dx.doi.org/10.1038/cddis.2012.114