Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways

Melanoma is an aggressive and drug-resistant cancer in need of improved therapeutic strategies. Restored expression of transcriptionally silenced genes is a potential approach, but it is limited by the genetic diversity of the melanoma tumors. The atypical heat shock protein H11/HspB8 has kinase act...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, C C, Lee, K S, Li, B, Laing, J M, Hersl, J, Shvartsbeyn, M, Aurelian, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434666/
https://www.ncbi.nlm.nih.gov/pubmed/22898869
http://dx.doi.org/10.1038/cddis.2012.108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434666/
https://www.ncbi.nlm.nih.gov/pubmed/22898869
http://dx.doi.org/10.1038/cddis.2012.108

Ejemplares similares