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Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways

Melanoma is an aggressive and drug-resistant cancer in need of improved therapeutic strategies. Restored expression of transcriptionally silenced genes is a potential approach, but it is limited by the genetic diversity of the melanoma tumors. The atypical heat shock protein H11/HspB8 has kinase act...

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Detalles Bibliográficos
Autores principales:	Smith, C C, Lee, K S, Li, B, Laing, J M, Hersl, J, Shvartsbeyn, M, Aurelian, L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434666/ https://www.ncbi.nlm.nih.gov/pubmed/22898869 http://dx.doi.org/10.1038/cddis.2012.108

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