The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress

Falcarindiol (FAD) is a natural polyyne with various beneficial biological activities. We show here that FAD preferentially kills colon cancer cells but not normal colon epithelial cells. Furthermore, FAD inhibits tumor growth in a xenograft tumor model and exhibits strong synergistic killing of can...

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Detalles Bibliográficos
Autores principales: Jin, H R, Zhao, J, Zhang, Z, Liao, Y, Wang, C-Z, Huang, W-H, Li, S-P, He, T-C, Yuan, C-S, Du, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434669/
https://www.ncbi.nlm.nih.gov/pubmed/22914324
http://dx.doi.org/10.1038/cddis.2012.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434669/
https://www.ncbi.nlm.nih.gov/pubmed/22914324
http://dx.doi.org/10.1038/cddis.2012.122

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