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Uncoupling the roles of synaptotagmin I as a dual Ca(2+) sensor during endo- and exocytosis of synaptic vesicles
Synaptotagmin I (syt1) is required for normal rates of synaptic vesicle endo- and exocytosis. However, whether the kinetic defects observed during endocytosis in syt1 knock-out neurons are secondary to defective exocytosis, or whether syt1 directly regulates the rate of vesicle retrieval, remains un...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435110/ https://www.ncbi.nlm.nih.gov/pubmed/22197832 http://dx.doi.org/10.1038/nn.3013 |