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Real-time Transcriptional Profiling of Cellular and Viral Gene Expression during Lytic Cytomegalovirus Infection

During viral infections cellular gene expression is subject to rapid alterations induced by both viral and antiviral mechanisms. In this study, we applied metabolic labeling of newly transcribed RNA with 4-thiouridine (4sU-tagging) to dissect the real-time kinetics of cellular and viral transcriptio...

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Detalles Bibliográficos
Autores principales: Marcinowski, Lisa, Lidschreiber, Michael, Windhager, Lukas, Rieder, Martina, Bosse, Jens B., Rädle, Bernd, Bonfert, Thomas, Györy, Ildiko, de Graaf, Miranda, da Costa, Olivia Prazeres, Rosenstiel, Philip, Friedel, Caroline C., Zimmer, Ralf, Ruzsics, Zsolt, Dölken, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435240/
https://www.ncbi.nlm.nih.gov/pubmed/22969428
http://dx.doi.org/10.1371/journal.ppat.1002908