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Integrative Genomic Analysis Identifies Isoleucine and CodY as Regulators of Listeria monocytogenes Virulence

Intracellular bacterial pathogens are metabolically adapted to grow within mammalian cells. While these adaptations are fundamental to the ability to cause disease, we know little about the relationship between the pathogen's metabolism and virulence. Here we used an integrative Metabolic Analy...

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Detalles Bibliográficos
Autores principales: Lobel, Lior, Sigal, Nadejda, Borovok, Ilya, Ruppin, Eytan, Herskovits, Anat A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435247/
https://www.ncbi.nlm.nih.gov/pubmed/22969433
http://dx.doi.org/10.1371/journal.pgen.1002887