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Ifitm3 Limits the Severity of Acute Influenza in Mice

Interferon-induced transmembrane (IFITM) proteins are a family of viral restriction factors that inhibit the entry processes of several pathogenic viruses, including influenza A virus (IAV), in vitro. Here we report that IAV-infected knockout mice lacking the Ifitm locus on chromosome 7 exhibited ac...

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Detalles Bibliográficos
Autores principales: Bailey, Charles C., Huang, I-Chueh, Kam, Christina, Farzan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435252/
https://www.ncbi.nlm.nih.gov/pubmed/22969429
http://dx.doi.org/10.1371/journal.ppat.1002909