Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response

Rhinovirus (RV) infection is a major cause of asthma exacerbations which may be due to a deficient innate immune response in the bronchial epithelium. We hypothesized that the pleiotropic cytokine, TGF-β, influences interferon (IFN) production by primary bronchial epithelial cells (PBECs) following...

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Detalles Bibliográficos
Autores principales: Bedke, Nicole, Sammut, David, Green, Ben, Kehagia, Valia, Dennison, Patrick, Jenkins, Gisli, Tatler, Amanda, Howarth, Peter H., Holgate, Stephen T., Davies, Donna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435262/
https://www.ncbi.nlm.nih.gov/pubmed/22970254
http://dx.doi.org/10.1371/journal.pone.0044580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435262/
https://www.ncbi.nlm.nih.gov/pubmed/22970254
http://dx.doi.org/10.1371/journal.pone.0044580

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