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Phosphorylation and Subcellular Localization of p27Kip1 Regulated by Hydrogen Peroxide Modulation in Cancer Cells

The Cyclin-dependent kinase inhibitor 1B (p27Kip1) is a key protein in the decision between proliferation and cell cycle exit. Quiescent cells show nuclear p27Kip1, but this protein is exported to the cytoplasm in response to proliferating signals. We recently reported that catalase treatment increa...

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Detalles Bibliográficos
Autores principales: Ibañez, Irene L., Bracalente, Candelaria, Notcovich, Cintia, Tropper, Ivanna, Molinari, Beatriz L., Policastro, Lucía L., Durán, Hebe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435274/
https://www.ncbi.nlm.nih.gov/pubmed/22970236
http://dx.doi.org/10.1371/journal.pone.0044502