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Phosphorylation and Subcellular Localization of p27Kip1 Regulated by Hydrogen Peroxide Modulation in Cancer Cells
The Cyclin-dependent kinase inhibitor 1B (p27Kip1) is a key protein in the decision between proliferation and cell cycle exit. Quiescent cells show nuclear p27Kip1, but this protein is exported to the cytoplasm in response to proliferating signals. We recently reported that catalase treatment increa...
Autores principales: | Ibañez, Irene L., Bracalente, Candelaria, Notcovich, Cintia, Tropper, Ivanna, Molinari, Beatriz L., Policastro, Lucía L., Durán, Hebe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435274/ https://www.ncbi.nlm.nih.gov/pubmed/22970236 http://dx.doi.org/10.1371/journal.pone.0044502 |
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