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The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance

The molecular chaperone Hsp90 orchestrates regulatory circuitry governing fungal morphogenesis, biofilm development, drug resistance, and virulence. Hsp90 functions in concert with co-chaperones to regulate stability and activation of client proteins, many of which are signal transducers. Here, we c...

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Detalles Bibliográficos
Autores principales: Shapiro, Rebecca S., Zaas, Aimee K., Betancourt-Quiroz, Marisol, Perfect, John R., Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435277/
https://www.ncbi.nlm.nih.gov/pubmed/22970302
http://dx.doi.org/10.1371/journal.pone.0044734