Distinct Effects of Rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on Cellular Bioenergetics and Cell Death

Parkinson’s disease is characterized by dopaminergic neurodegeneration and is associated with mitochondrial dysfunction. The bioenergetic susceptibility of dopaminergic neurons to toxins which induce Parkinson’s like syndromes in animal models is then of particular interest. For example, rotenone, 1...

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Detalles Bibliográficos
Autores principales: Giordano, Samantha, Lee, Jisun, Darley-Usmar, Victor M., Zhang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435291/
https://www.ncbi.nlm.nih.gov/pubmed/22970265
http://dx.doi.org/10.1371/journal.pone.0044610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435291/
https://www.ncbi.nlm.nih.gov/pubmed/22970265
http://dx.doi.org/10.1371/journal.pone.0044610

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