The Differential Effect of NAT2 Variant Alleles Permits Refinement in Phenotype Inference and Identifies a Very Slow Acetylation Genotype

Indirect evidences suggest that acetylation phenotype categories are heterogeneous and that subcategories, related to specific NAT2 variant alleles might exist. We analyzed the in vivo acetylation phenotype and genotype in 504 north-American subjects of Caucasian origin. The analyses of the SNPs rs1...

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Detalles Bibliográficos
Autores principales: Ruiz, Jhon D., Martínez, Carmen, Anderson, Kristin, Gross, Myron, Lang, Nicholas P., García-Martín, Elena, Agúndez, José A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435299/
https://www.ncbi.nlm.nih.gov/pubmed/22970273
http://dx.doi.org/10.1371/journal.pone.0044629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435299/
https://www.ncbi.nlm.nih.gov/pubmed/22970273
http://dx.doi.org/10.1371/journal.pone.0044629

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