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The Differential Effect of NAT2 Variant Alleles Permits Refinement in Phenotype Inference and Identifies a Very Slow Acetylation Genotype
Indirect evidences suggest that acetylation phenotype categories are heterogeneous and that subcategories, related to specific NAT2 variant alleles might exist. We analyzed the in vivo acetylation phenotype and genotype in 504 north-American subjects of Caucasian origin. The analyses of the SNPs rs1...
Autores principales: | Ruiz, Jhon D., Martínez, Carmen, Anderson, Kristin, Gross, Myron, Lang, Nicholas P., García-Martín, Elena, Agúndez, José A. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435299/ https://www.ncbi.nlm.nih.gov/pubmed/22970273 http://dx.doi.org/10.1371/journal.pone.0044629 |
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