Development of Multicellular Tumor Spheroid (MCTS) Culture from Breast Cancer Cell and a High Throughput Screening Method Using the MTT Assay

In comparison to monolayer cells, MCTS has been claimed as more suitable candidate for studying drug penetration due to the high resemblance to solid tumors. However, the cultivation of MCTS is cumbersome, time consuming, and most technique fail to generate spheroids with uniform sizes. Therefore, t...

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Detalles Bibliográficos
Autores principales: Ho, Wan Yong, Yeap, Swee Keong, Ho, Chai Ling, Rahim, Raha Abdul, Alitheen, Noorjahan Banu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435305/
https://www.ncbi.nlm.nih.gov/pubmed/22970274
http://dx.doi.org/10.1371/journal.pone.0044640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435305/
https://www.ncbi.nlm.nih.gov/pubmed/22970274
http://dx.doi.org/10.1371/journal.pone.0044640

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