Genomic DNA Copy-Number Alterations of the let-7 Family in Human Cancers

In human cancer, expression of the let-7 family is significantly reduced, and this is associated with shorter survival times in patients. However, the mechanisms leading to let-7 downregulation in cancer are still largely unclear. Since an alteration in copy-number is one of the causes of gene dereg...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yanling, Hu, Xiaowen, Greshock, Joel, Shen, Liang, Yang, Xiaojun, Shao, Zhongjun, Liang, Shun, Tanyi, Janos L., Sood, Anil K., Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435307/
https://www.ncbi.nlm.nih.gov/pubmed/22970210
http://dx.doi.org/10.1371/journal.pone.0044399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435307/
https://www.ncbi.nlm.nih.gov/pubmed/22970210
http://dx.doi.org/10.1371/journal.pone.0044399

Ejemplares similares