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Optimisation of Prime–Boost Immunization in Mice Using Novel Protein-Based and Recombinant Vaccinia (Tiantan)-Based HBV Vaccine

BACKGROUND: A therapeutic vaccine for chronic hepatitis B virus (HBV) infection that enhances virus-specific cellular immune responses is urgently needed. The “prime–boost” regimen is a widely used vaccine strategy against many persistence infections. However, few reports have addressed this strateg...

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Detalles Bibliográficos
Autores principales: Chen, Hong, Chuai, Xia, Deng, Yao, Wen, Bo, Wang, Wen, Xiong, Shaoqing, Ruan, Li, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435326/
https://www.ncbi.nlm.nih.gov/pubmed/22970140
http://dx.doi.org/10.1371/journal.pone.0043730