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A Fluorescent, Genetically-Encoded Voltage Probe Capable of Resolving Action Potentials

There is a pressing need in neuroscience for genetically-encoded, fluorescent voltage probes that can be targeted to specific neurons and circuits to allow study of neural activity using fluorescent imaging. We created 90 constructs in which the voltage sensing portion (S1–S4) of Ciona intestinalis...

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Detalles Bibliográficos
Autores principales: Barnett, Lauren, Platisa, Jelena, Popovic, Marko, Pieribone, Vincent A., Hughes, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435330/
https://www.ncbi.nlm.nih.gov/pubmed/22970127
http://dx.doi.org/10.1371/journal.pone.0043454