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Synthesis and Evaluation of a Conjugate Vaccine Composed of Staphylococcus aureus Poly-N-Acetyl-Glucosamine and Clumping Factor A

The increasing frequency, severity and antimicrobial resistance of Staphylococcus aureus infections has made the development of immunotherapies against this pathogen more urgent than ever. Previous immunization attempts using monovalent antigens resulted in at best partial levels of protection again...

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Detalles Bibliográficos
Autores principales: Maira-Litrán, Tomás, Bentancor, Leticia V., Bozkurt-Guzel, Cagla, O'Malley, Jennifer M., Cywes-Bentley, Colette, Pier, Gerald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435376/
https://www.ncbi.nlm.nih.gov/pubmed/22970144
http://dx.doi.org/10.1371/journal.pone.0043813