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Improved Minimum Cost and Maximum Power Two Stage Genome-Wide Association Study Designs
In a two stage genome-wide association study (2S-GWAS), a sample of cases and controls is allocated into two groups, and genetic markers are analyzed sequentially with respect to these groups. For such studies, experimental design considerations have primarily focused on minimizing study cost as a f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435377/ https://www.ncbi.nlm.nih.gov/pubmed/22970116 http://dx.doi.org/10.1371/journal.pone.0042367 |