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Identification and Characterization of B-Cell Epitopes in the DBL4ε Domain of VAR2CSA

Malaria during pregnancy in Plasmodium falciparum endemic regions is a major cause of mortality and severe morbidity. VAR2CSA is the parasite ligand responsible for sequestration of Plasmodium falciparum infected erythrocytes to the receptor chondroitin sulfate A (CSA) in the placenta and is the lea...

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Detalles Bibliográficos
Autores principales: Ditlev, Sisse B., Nielsen, Morten A., Resende, Mafalda, Agerbæk, Mette Ø., Pinto, Vera V., Andersen, Pernille H., Magistrado, Pamela, Lusingu, John, Dahlbäck, Madeleine, Theander, Thor G., Salanti, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435390/
https://www.ncbi.nlm.nih.gov/pubmed/22970138
http://dx.doi.org/10.1371/journal.pone.0043663