Analysis of Candidate Colitis Genes in the Gdac1 Locus of Mice Deficient in Glutathione Peroxidase-1 and -2

BACKGROUND: Mice that are deficient for glutathione peroxidases 1 and 2 (GPX) show large variations in the penetrance and severity of colitis in C57BL/6J and 129S1/SvImJ backgrounds. We mapped a locus contributing to this difference to distal chromosome 2 (∼119–133 mbp) and named it glutathione pero...

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Detalles Bibliográficos
Autores principales: Esworthy, R. Steven, Kim, Byung-Wook, Rivas, Guillermo E., Leto, Thomas L., Doroshow, James H., Chu, Fong-Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435402/
https://www.ncbi.nlm.nih.gov/pubmed/22970191
http://dx.doi.org/10.1371/journal.pone.0044262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435402/
https://www.ncbi.nlm.nih.gov/pubmed/22970191
http://dx.doi.org/10.1371/journal.pone.0044262

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