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α-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways

α-Tomatine, a tomato glycoalkaloid, has been reported to possess antibiotic properties against human pathogens. However, the mechanism of its action against leukemia remains unclear. In this study, the therapeutic potential of α-tomatine against leukemic cells was evaluated in vitro and in vivo. Cel...

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Detalles Bibliográficos
Autores principales: Chao, Min-Wu, Chen, Chun-Han, Chang, Ya-Ling, Teng, Che-Ming, Pan, Shiow-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435411/
https://www.ncbi.nlm.nih.gov/pubmed/22970166
http://dx.doi.org/10.1371/journal.pone.0044093