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PV1 down-regulation via shRNA inhibits the growth of pancreatic adenocarcinoma xenografts

PV1 is an endothelial-specific protein with structural roles in the formation of diaphragms in endothelial cells of normal vessels. PV1 is also highly expressed on endothelial cells of many solid tumours. On the basis of in vitro data, PV1 is thought to actively participate in angiogenesis. To test...

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Detalles Bibliográficos
Autores principales: Deharvengt, Sophie J, Tse, Dan, Sideleva, Olga, McGarry, Caitlin, Gunn, Jason R, Longnecker, Daniel S, Carriere, Catherine, Stan, Radu V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435473/
https://www.ncbi.nlm.nih.gov/pubmed/22568538
http://dx.doi.org/10.1111/j.1582-4934.2012.01587.x