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The Deubiquitylase USP37 Links REST to the Control of p27 Stability and Cell Proliferation

The RE1 Silencing Transcription Factor (REST) is a repressor of neuronal differentiation and its elevated expression in neural cells blocks neuronal differentiation. In the present study, we demonstrate a role for REST in the control of proliferation of medulloblastoma cells. REST expression decreas...

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Detalles Bibliográficos
Autores principales: Das, Chandra M., Taylor, Pete, Gireud, Monica, Singh, Akanksha, Lee, Dean, Fuller, Greg, Ji, Lingyun, Fangusaro, Jason, Rajaram, Veena, Goldman, Stewart, Eberhart, Charles, Gopalakrishnan, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435483/
https://www.ncbi.nlm.nih.gov/pubmed/22665064
http://dx.doi.org/10.1038/onc.2012.182