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Regulation of Glycolysis and the Warburg Effect by Estrogen-related Receptors

Cancer cells typically display altered glucose metabolism characterized by a preference of aerobic glycolysis, known as the Warburg effect, which facilitates cell proliferation. Hypoxia-inducible factor (HIF) and oncoprotein Myc are two prominent transcription factors that drive glycolysis. Previous...

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Detalles Bibliográficos
Autores principales: Cai, Qingsong, Lin, Tong, Kamarajugadda, Sushama, Lu, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435484/
https://www.ncbi.nlm.nih.gov/pubmed/22665055
http://dx.doi.org/10.1038/onc.2012.221