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Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS

Understanding the genetic basis of gene regulatory variation is a key goal of evolutionary and medical genetics. Regulatory variation can act in an allele-specific manner (cis-acting) or it can affect both alleles of a gene (trans-acting). Differential allele-specific expression (ASE), in which the...

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Detalles Bibliográficos
Autores principales: Khan, Zia, Bloom, Joshua S, Amini, Sasan, Singh, Mona, Perlman, David H, Caudy, Amy A, Kruglyak, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435501/
https://www.ncbi.nlm.nih.gov/pubmed/22893000
http://dx.doi.org/10.1038/msb.2012.34