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Mapping the human phosphatome on growth pathways

Large-scale siRNA screenings allow linking the function of poorly characterized genes to phenotypic readouts. According to this strategy, genes are associated with a function of interest if the alteration of their expression perturbs the phenotypic readouts. However, given the intricacy of the cell...

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Detalles Bibliográficos
Autores principales: Sacco, Francesca, Gherardini, Pier Federico, Paoluzi, Serena, Saez-Rodriguez, Julio, Helmer-Citterich, Manuela, Ragnini-Wilson, Antonella, Castagnoli, Luisa, Cesareni, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435503/
https://www.ncbi.nlm.nih.gov/pubmed/22893001
http://dx.doi.org/10.1038/msb.2012.36