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Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma

Large-scale cancer genomics projects are profiling hundreds of tumors at multiple molecular layers, including copy number, mRNA and miRNA expression, but the mechanistic relationships between these layers are often excluded from computational models. We developed a supervised learning framework for...

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Detalles Bibliográficos
Autores principales: Setty, Manu, Helmy, Karim, Khan, Aly A, Silber, Joachim, Arvey, Aaron, Neezen, Frank, Agius, Phaedra, Huse, Jason T, Holland, Eric C, Leslie, Christina S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435504/
https://www.ncbi.nlm.nih.gov/pubmed/22929615
http://dx.doi.org/10.1038/msb.2012.37