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Behavioral characterization of mice lacking Trek channels

Two-pore domain K(+) (K(2P)) channels are thought to underlie background K(+) conductance in many cell types. The Trek subfamily of K(2P) channels consists of three members, Trek1/Kcnk2, Trek2/Kcnk10, and Traak/Kcnk4, all three of which are expressed in the rodent CNS. Constitutive ablation of the T...

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Detalles Bibliográficos
Autores principales: Mirkovic, Kelsey, Palmersheim, Jaime, Lesage, Florian, Wickman, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435516/
https://www.ncbi.nlm.nih.gov/pubmed/22973213
http://dx.doi.org/10.3389/fnbeh.2012.00060