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High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation

Macrophage foam cells are a defining pathologic feature of atherosclerotic lesions. Recent studies have demonstrated that at high concentrations associated with hypercholesterolemia, native LDL induces macrophage lipid accumulation. LDL particles are taken up by macrophages as part of bulk fluid pin...

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Detalles Bibliográficos
Autores principales: Meyer, Jason M., Ji, Ailing, Cai, Lei, van der Westhuyzen, Deneys R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435541/
https://www.ncbi.nlm.nih.gov/pubmed/22833685
http://dx.doi.org/10.1194/jlr.M026534