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The influence of active transport systems on morphine -6-glucuronide transport in MDCKII and MDCK-PGP cells

BACKGROUND AND THE PURPOSE OF THE STUDY: Morphine-6-glucuronide (M6G) is a potent metabolite of morphine which has high penetration into the brain despite its high polarity, which could be the result of an active transport system involved in M6G transport through blood brain barrier. Examples of suc...

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Detalles Bibliográficos
Autores principales: Sattari, M., Routledge, PA., Mashayekhi, SO.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436077/
https://www.ncbi.nlm.nih.gov/pubmed/23008686