Cargando…
The influence of active transport systems on morphine -6-glucuronide transport in MDCKII and MDCK-PGP cells
BACKGROUND AND THE PURPOSE OF THE STUDY: Morphine-6-glucuronide (M6G) is a potent metabolite of morphine which has high penetration into the brain despite its high polarity, which could be the result of an active transport system involved in M6G transport through blood brain barrier. Examples of suc...
Autores principales: | Sattari, M., Routledge, PA., Mashayekhi, SO. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436077/ https://www.ncbi.nlm.nih.gov/pubmed/23008686 |
Ejemplares similares
-
Evidence of active transport involvement in morphine transport via MDCKII and MDCK-PGP cell lines
por: Mashayekhi, S.O., et al.
Publicado: (2010) -
Impact of anti-cancer drugs and other determinants on serum protein binding of morphine 6-glucuronide
por: Mashayekhi, S.O., et al.
Publicado: (2010) -
Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide
por: de Hoogd, Sjoerd, et al.
Publicado: (2017) -
Pharmacokinetics of Morphine, Morphine-3-Glucuronide and Morphine-6-Glucuronide in Terminally Ill Adult Patients
por: Franken, Linda G., et al.
Publicado: (2015) -
Explanation at the opioid receptor level for differing toxicity of morphine and morphine 6-glucuronide.
por: Hucks, D., et al.
Publicado: (1992)