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Systematic protein-protein docking and molecular dynamics studies of HIV-1 gp120 and CD4: insights for new drug development
BACKGROUND AND THE PURPOSE OF THE STUDY: The interactions between HIV-1 gp120 and mutated CD4 proteins were investigated in order to identify a lead structure for therapy based on competitive blocking of the HIV binding receptor for human T-cells. Crystal structures of HIV gp120-CD4 complexes reveal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Tehran University of Medical Sciences
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436085/ https://www.ncbi.nlm.nih.gov/pubmed/23008694 |